| Creators: |
Reinehr, Thomas and Schnabel, Dirk and Wabitsch, Martin and Bechtold, Susanne and Bührer, Christoph and Heidtmann, Bettina and Jochum, Frank and Kauth, Thomas and Körner, Antje and Mihatsch, Walter and Prell, Christine and Rudloff, Silvia and Tittel, Bettina and Wölfle, Joachim and Zimmer, Klaus-Peter and Koletzko, Berthold |
| Abstract (ENG): |
Background: Low vitamin D serum concentrations have been associated with rickets and other disorders in observational studies. Since vitamin D serum concentrations in children and adolescents are frequently below reference values, it is debated whether vitamin D should be supplemented after infancy. Methods: The effects of vitamin D supplementation in children > 2 years of age are analyzed based on a literature review of randomized controlled trials (RCTs). Results: Vitamin D supplementation can potentially reduce the risk for influenza infections and improve asthma bronchiale exacerbation; however, it has no impact on asthma bronchiale severity. Vitamin D supplementation has no relevant effect on attention-deficit/hyperactivity disorders, cardiac failure, hypertension, or incidence of type II diabetes mellitus. Vitamin D supplementation has no effect on the rate of multiple sclerosis relapses, but on the number of new lesions detected by MRI. For other endpoints, RCTs are lacking. Conclusion Based on currently available studies, routine vitamin D supplementation is not be recommended for children aged > 2 years, even when they have serum concentrations below reference values. Routine vitamin D supplementation is not recommended in children who do not have risk factors and chronic diseases which are associated with calcium or vitamin D resorption disorders. |
| Citation: |
Reinehr, Thomas and Schnabel, Dirk and Wabitsch, Martin and Bechtold, Susanne and Bührer, Christoph and Heidtmann, Bettina and Jochum, Frank and Kauth, Thomas and Körner, Antje and Mihatsch, Walter and Prell, Christine and Rudloff, Silvia and Tittel, Bettina and Wölfle, Joachim and Zimmer, Klaus-Peter and Koletzko, Berthold
(2019)
Vitamin D supplementation after the second year of life: joint position of the Committee on Nutrition, German Society for Pediatric and Adolescent Medicine (DGKJ e.V.), and the German Society for Pediatric Endocrinology and Diabetology (DGKED e.V.).
Molecular and Cellular Pediatrics : official journal of The German Society of Pediatrics and Adolescent Medicine, 6 (3).
ISSN 2194-7791
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