| Creators: |
Stenzinger, Albrecht and Edsjö, Anders and Ploeger, Carolin and Friedman, Mikaela and Fröhling, Stefan and Wirta, Valtteri and Seufferlein, Thomas and Botling, Johan and Duyster, Justus and Akhras, Michael and Thimme, Robert and Fioretos, Thoas and Bitzer, Michael and Cavelier, Lucia and Schirmacher, Peter and Malek, Nisar and Rosenquist, Richard and GMS Working Group and ZPM Working Group |
| Abstract (ENG): |
Over the last decades, rapid technological and scientific advances have led to a merge of molecular sciences and clinical medicine, resulting in a better understanding of disease mechanisms and the development of novel therapies that exploit specific molecular lesions or profiles driving disease. Precision oncology is here used as an example, illustrating the potential of precision/personalized medicine that also holds great promise in other medical fields. Real-world implementation can only be achieved by dedicated healthcare connected centers which amass and build up interdisciplinary expertise reflecting the complexity of precision medicine. Networks of such centers are ideally suited for a nation-wide outreach offering access to precision medicine to patients independent of their place of residence. Two of these multicentric initiatives, Genomic Medicine Sweden (GMS) and the Centers for Personalized Medicine (ZPM) initiative in Germany have teamed up to present and share their views on core concepts, potentials, challenges, and future developments in precision medicine. Together with other initiatives worldwide, GMS and ZPM aim at providing a robust and sustainable framework, covering all components from technology development to clinical trials, ethical and legal aspects as well as involvement of all relevant stakeholders, including patients and policymakers in the field. |
| Citation: |
Stenzinger, Albrecht and Edsjö, Anders and Ploeger, Carolin and Friedman, Mikaela and Fröhling, Stefan and Wirta, Valtteri and Seufferlein, Thomas and Botling, Johan and Duyster, Justus and Akhras, Michael and Thimme, Robert and Fioretos, Thoas and Bitzer, Michael and Cavelier, Lucia and Schirmacher, Peter and Malek, Nisar and Rosenquist, Richard and GMS Working Group and ZPM Working Group
(2022)
Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany.
Seminars in Cancer Biology, 84.
pp. 242-254.
ISSN 1096-3650
|
